Evaporative Light Scattering Detector
Enhanced Sensitivity for Trace Analysis
The ELSD-LTII utilizes a high-efficiency LED and enhanced digital signal/
treatment to minimize noise and deliver optimum sensitivity for trace analysis.
An innovative cell design also reduces band broadening and allows sensitivity
levels below 200 picograms. The high-performance optical detection system
can also be used for combinatorial chemistry and high-throughput screening
applications. The new Low Temperature Evaporative Light Scattering Detector
(ELSD-LTII) is an easy-to-operate, universal detector that identifies analytes with
uniform sensitivity regardless of their spectroscopic properties. It is not a
spectroscopic detector. Instead, it removes the mobile phase through evaporation
and then makes a light scattering measurement of the dried analyte particles.
The ELSD-LTII is ideally suited for such applications as drug discovery, natural products development, combinatorial chemistry, and food and beverage. It will enable you to see all sample components, even semi-volatile compounds, down to the high picogram level.
The ELSD-LTII provides excellent performance during gradients for optimized separations and reduced run times. A unique cell design reduces band broadening to a level similar to UV-Vis detectors while its single mode, low-temperature operation (user defined from ambient 80°C) optimizes sensitivity for those analytes that are easily missed at higher evaporation temperatures typical of competing detectors.
|A Universal Detector||Detects all semi- and non-volatile analytes in your sample, including those transparent to other detectors.|
|Fully Gradient Compatible||Handles any combination of volatile mobile phases and gradients for powerful separations and minimized run times.|
|Higher Sensitivity than RI and other ELSDs on the market||The ELSD-LTII is 10 - 100X more sensitive than RI detectors for all samples and under all mobile phase conditions.|
|Detects all analytes, including semi-volatiles, at near-ambient evaporation temperatures||Absolute temperature range (Ambient - 80°C) Commonly used working range (Ambient - 40°C) Semi-volatile analytes and compounds that thermally decompose are easily missed with competing detectors.|
|Accepts a wide range of mobile phase flows||The ELSD-LTII displays excellent signal/noise characteristics over solvent flows from 100µL/min. to 4.0 mL/min.|
|Single-Mode operation||Low temperature operation without accessories, separate operating modes. Most analyses are done using a common set of conditions (Gain 5; Temp 40°C; P 350kPa).|
|Time program air/nitrogen shutoff||A time program method may be used to shut off the inlet gas, ending the problem of wasted gas after work is done.|
|Unique nebulizer/drift tube design offers protection from "fouling"||The nebulizer and drift tube are separated by a glass chamber which protects the evaporation and detection stages from particle buildup. In competing detectors, such buildup contributes to background noise that cannot be solved without maintenance.|
|Stack other detectors on top of the ELSD-LTII||The ELSD-LTII fits perfectly into the modular design of Shimadzu Prominence HPLC hardware. Dimensions: W250 x H450 x D550mm|
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